Dr. Annie Huang is a pediatric neuro-oncologist, Senior Scientist in the Cell Biology Program (CB), and the Arthur and Sonia Labatt Brain Tumour Research Centre (BTRC), at The Hospital for Sick Children (SickKids), Toronto, Canada. She is a Professor of Pediatrics, Medical Biophysics, Laboratory Medicine & Pathobiology and serves as the Associate Chair for Research, Dept of Pediatrics, University of Toronto. She holds a Tier 1 Canada Research Chair in Rare Childhood Brain Tumors.

Dr. Huang’s clinical and research expertise is in high-risk, high-fatality, rare childhood brain cancers arising in young children. She is the founder and lead investigator of the International Rare Brain Tumour Consortium, comprised of 130+ collaborative centres that contribute to a clinical registry and biorepository. The unique RBTC collaborative network and resources has enabled sentinel large scale studies of these rare diseases which informed the revised WHO molecular-based classification of CNS tumors. Her lab research, which focuses on understanding the molecular pathogenesis of rare brain tumors, has significantly advanced diagnosis, therapeutic and mechanistic understanding of ATRT, ETMR and Pineoblastoma which collectively comprise most rare paediatric embryonal brain tumours. Dr Huang’s lab discovered the C19MC microRNA cluster as a novel oncogene, and diagnostic marker for ETMRs, and were amongst the first to uncover molecular sub-groups of ATRTs and Pineoblastoma. In addition to her clinical and laboratory work, Dr. Huang serves as the Biology Studies Chair for the CNS Tumor Committee of COG – Childrens Oncology Group, the world’s largest paediatric cancer trial consortium where she contributes to development of biology-based clinical trials for all CNS tumours. She also served as the Pediatric Board Representative and first Pediatric Track Lead for the Society of NeuroOncology, and as an associate editor on Neuro-Oncology and NeuroOncology Advances, two leading journals in the field of brain tumors.

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