Dr. Kline is a pediatric neuro-oncology attending and Director of Neuro-Oncology Clinical Research at the Children’s Hospital of Philadelphia (CHOP). Dr. Kline completed her residency in pediatrics at CHOP followed by a fellowship in pediatric hematology-oncology at the University of California San Francisco (UCSF). While at UCSF, Dr. Kline completed a Master’s in Clinical Research and subsequently stayed on as early faculty before returning to CHOP in her current role. Dr. Kline’s academic focus is clinical research and early phase trial development for pediatric central nervous system tumors, with a particular focus on diffuse midline gliomas (DMG) and craniopharyngioma. To this end, she currently leads or co-leads several clinical trials dedicated to novel therapies for children and young adults with DMG and craniopharyngioma, bringing together novel drugs, new therapy combinations, and investigational drug delivery systems. In addition to the above work, Dr. Kline serves as the Project Co-Leader and Director of Data Quality and Integration for the Pediatric Neuro-Oncology Consortium (PNOC), a global clinical trials consortium; member of the Children’s Brain Tumor Network (CBTN) Scientific Committee and Executive Board, a global pediatric brain tumor data and biorepository; and co-lead of both the CHOP Cancer Center Health Equity Committee and PNOC/CBTN Health Equity and Craniopharyngioma working groups. Most recently, Dr. Kline has embarked on creating a new non-profit organization, Golden Thread, a physician-led organization committed to finding new cures in pediatric cancer through cross-sector collaborations, creative funding strategies, and partnership with policy-makers.