Dr. Uri Tabori is the head of the Neuro-Oncology program at the Hospital for Sick Children and a Garron Family Chair appointment in Childhood Cancer Research. Dr Tabori is a Professor in the Departments of Medical Biophysics and Institute of Medical Science and Paediatrics, University of Toronto.

Based on his clinical background and expertise, his research focuses on translational aspects of cancer originating from patients need, through basic discoveries and clinical trials to changes in how society is managing specific cancers. Specifically, Dr Tabori focuses on the development of systems for early detection, intervention and therapeutics in children and young adults highly predisposed to developing brain tumors and the approach to low grade gliomas. 

Dr Tabori leads the international Replication Repair Deficiency consortium which is supporting patients and families in diagnosis, management and therapies in >50 countries. The consortium is running international clinical trials for children with hypermutant cancers with immune checkpoint inhibitors and combinations. Dr Tabori is also developing animal models and companion biomarker designed for immunotherapy therapeutics.

Dr Tabori also co-leads the pediatric low grade glioma taskforce which uncovers novel alterations in this most common brain tumor in children and offers targeted therapies and trials. He is responsible for the development of companion biomarkers to these trials.

Using these consortia, Dr Tabori and colleagues are focusing on using the immune system for cancer interception and prevention in children and young adults.

Dr. Tabori has been the recipient of numerous awards, including the Canadian Cancer Society’s Bernard and Francine Dorval Prize in  and the Early Researcher Award from the Ontario Ministry of Development in Innovation. He has >300 peer reviewed publications and holds research grants from various international and national agencies the NIH, DOD, CIHR, Terry Fox, V-foundation, the Anti Cancer fund among others.